Hoʻohana nui ʻia nā peʻa magnetic i ka maʻi immune, ka maʻi molecular, ka hoʻomaʻemaʻe protein, ka hoʻokaʻawale ʻana i nā cell, a me nā māla ʻē aʻe.
Immunodiagnosis: Hoʻokumu ʻia nā pēke immunomagnetic me nā ʻāpana magnetic a me nā mea me nā pūʻulu hana ikaika.Hoʻohui pū ʻia nā ligand protein (antigens a i ʻole antibodies) i nā pūʻulu hana o nā peʻa magnetic, a laila hana ʻia ka immunoassay me ka hoʻohana ʻana i nā paʻina protein bead magnetic.
Maikaʻi Molecular (Nucleic acid extraction): Nanoscale magnetic beads with surface groups that can adsorb nucleic acid can be separated and adsorbed by a magnetic field, and then eluted to get template nucleic acid.
Ka hoʻomaʻemaʻe ʻana i ka protein: ʻO ka agarose i hoʻopili ʻia i hui pū ʻia me ka protein fusion recombinant A/G ma luna o ka ʻili o nā peʻa magnetic, kahi protein paʻa kikoʻī o ProteinA/G, a hoʻopau hope ʻia no ka loaʻa ʻana o nā antibodies i hoʻomaʻemaʻe ʻia.
ʻO ka hōʻoia ʻana o ka Immune a me ka ʻike molekula:
ʻO kekahi o nā noi koʻikoʻi o nā peʻa magnetic aia i ka maʻi immune, kahi i lilo ai lākou i mea pono pono no ka ʻike pololei ʻana i nā maʻi.ʻO ka hiʻohiʻona kūʻokoʻa o nā peʻa magnetic e ala mai i ko lākou hiki ke hopu a hoʻokaʻawale i nā antigens a i ʻole nā antibodies kūikawā mai nā laʻana maʻi, e hoʻomaʻamaʻa i ke kaʻina diagnostic.Ma ka hui pū ʻana i nā ligand protein, e like me nā antigens a i ʻole nā antibody, i nā pūʻulu hana o nā peʻa magnetic, hiki i nā mea noiʻi ke hana i nā immunoassays me ka maikaʻi a me ka pololei i hoʻonui ʻia.ʻO ka maʻi molecular, kahi kahua hoihoi ʻē aʻe, pōmaikaʻi nui mai ka hoʻohana ʻana i nā peʻa magnetic.Me nā ʻenehana diagnostic molecular e ʻike nui ʻia i nā makahiki i hala iho nei, he kuleana koʻikoʻi nā peʻa magnetic i ka hoʻokaʻawale ʻana a me ka unuhi ʻana i nā waikawa nucleic, e like me DNA a i ʻole RNA, mai nā laʻana olaola.Ke hana nei kēia mau lei ma ke ʻano he kākoʻo paʻa, e hoʻomaʻamaʻa i ka hopu ʻana a me ka hoʻomaʻemaʻe ʻana i nā molekole i loaʻa.ʻO kēia ala holomua i hiki ai i nā ʻepekema ke hoʻokō i ka hōʻoia pololei a hilinaʻi, e alakaʻi ana i nā hopena maʻi maikaʻi aʻe.
Hoʻomaʻemaʻe Protein a me ka hoʻokaʻawale ʻana i nā cell:
Loaʻa ka hoʻohana nui ʻana o nā peʻa magnetic i ka hoʻomaʻemaʻe protein, kahi hana koʻikoʻi i ka hoʻomohala lāʻau a me ka noiʻi biochemistry.Ma ka hoʻopili ʻana i nā ligand kikoʻī i nā peʻa, hiki i nā mea noiʻi ke hoʻopaʻa koho a unuhi i nā protein target me nā maʻemaʻe kiʻekiʻe a me nā hua.ʻO kēia kaʻina hana hoʻomaʻemaʻe e hoʻolalelale i ke kaʻina noiʻi holoʻokoʻa, e ʻae ana i nā ʻepekema e nānā a noiʻi i nā protein i kahi ʻano kikoʻī.ʻO ka wehe ʻana i ke kelepona, kahi mea nui o nā noiʻi lapaʻau a me nā noiʻi noiʻi, he kahua ʻē aʻe i pōmaikaʻi nui ʻia e nā pahu magnetic.ʻO kēia mau pahu, i hui pū ʻia me nā biomarkers a i ʻole antibodies, e hoʻomaʻamaʻa i ka hoʻokaʻawale ʻana a me ka hoʻokaʻawale ʻana o nā heluna cell like ʻole.Ma ka hoʻohana ʻana i kahi māla magnetic, hiki i nā ʻepekema ke hoʻokaʻawale a hoʻokaʻawale i nā cell ma muli o ko lākou ʻano kino a me ka hana.ʻO ka maʻalahi a me ka pololei o kēia ʻenehana ua hoʻoikaika i nā hana noiʻi i ka hoʻomaopopo ʻana i nā kaʻina kelepona paʻakikī, e like me ka piʻi ʻana o ka maʻi maʻi a me ka pane ʻana i ke kino.
Ka manawa hoʻouna: Iune-25-2023